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Medical Technologist I - Clinical Genomics

University of Illinois Chicago
United States, Illinois, Chicago
Nov 20, 2024


Medical Technologist I - Clinical Genomics

Medical Technologist I - Clinical Genomics

Hiring Department: Labs/Pathology Svcs

Location: Chicago, IL USA

Requisition ID: 1026728

Salary: $34.32-$45.21 hourly rate-commensurate with experience

Posting Close Date: 12/2/2024

About UI Health

The University of Illinois Hospital & Health Sciences System (UI Health) provides comprehensive care, education, and research to the people of Illinois and beyond. A part of the University of Illinois at Chicago (UIC), UI Health comprises a clinical enterprise that includes a 495-bed tertiary care hospital, 22 outpatient clinics, and 13 Mile Square Health Center facilities, which are Federally Qualified Health Centers. It also includes the seven UIC health science colleges: the College of Applied Health Sciences; the College of Dentistry; the School of Public Health; the Jane Addams College of Social Work; and the Colleges of Medicine, Pharmacy, and Nursing, including regional campuses in Peoria, Quad Cities, Rockford, Springfield, and Urbana. UI Health is dedicated to the pursuit of health equity.

Position Summary
A Medical Technologist in Clinical Genomics is expected to perform 1) clinical diagnostic testing which includes DNA sequence data analysis from high-complexity tests such as the solid tumor sequencing panel, the hematologic malignancies sequencing panel, and clinical exome sequencing; 2) perform variant curation and interpretation, develop protocols for variant curation and classification; and 3) participate in new test developments and clinical research projects. Perform CLIA clinical diagnostic testing with a variety of tests of a moderately or highly complex nature on patient and quality control samples for molecular pathology procedures.

Duties & Responsibilities

  • Perform highly and moderately complex tests by various analyzers in the Laboratory, and/or by manual methods, on various specimen sources such as blood, urine, and other body fluids, using established procedures, under close supervision. PCR Procedures to detect and quantitate RNA and DNA for various genomic markers. DNA sequencing on solid tumor/oncology specimens
  • Perform routine molecular pathology procedures as needed: Manual DNA/RNA extractions from whole blood, urine, saliva, cerebral spinal fluid, BAL and other body fluids as needed.
  • Automated Extractions: performs extraction of DNA and/or RNA extractions using an automated system and applies knowledge of extraction theory to troubleshoot system.
  • Preparation/Storage of reagents- prepares various reagents used for variety of molecular techniques such as PCR master mix and stores appropriately; apply knowledge of use of various pieces of equipment used in the preparation of reagents.
  • Manipulate and operate simple and complex laboratory equipment including computers and sequencers; perform maintenance and limited tear down and replacement of parts of laboratory equipment; problem-solve equipment malfunctions. Review test results before reporting, using technical and scientific knowledge to recognize and verify results. Consult with supervisor prior to the release of results when results are unusual or unanticipated. Notify patients' physician(s) of life-threatening results.
  • Perform established quality assurance procedures (i.e., quality control testing, instrument function checks and calibrations) and maintain appropriate records for these procedures.
  • Understand the statistics applied to the quality assurance program and review and maintain the records.
  • Knowledge in molecular biology related protocols (including DNA/RNA preparation and quantification, hybridization, PCR, multiplex amplification, Next Generation Sequencing required)
  • Solid understanding of genetics, NGS technology, and statistics. Data analysis including scripting, programming, statistical analyses. Use the laboratory information system for all records, functions and inquiries related to testing of patient specimens.
  • Performs molecular tests according to SOP for diagnostic and research samples. Performs research data gathering and downstream data processing and bioinformatics analysis. Complete Corrective Action Reports to thoroughly document any matter requiring follow-up or corrective action
  • Support and adhere to all CLIA and OSHA guidelines (OSHA Bloodborne Pathogens standards) and all regulatory standards of UIH.
  • Assists in the orientation and training of new employees. Participates in the training of technical staff and monitors their progress with supervisor. Interact with physicians, patients, staff, visitors and all customers via telephone conversations and in person in a pleasant and helpful manner.
  • Perform other related duties and participate in special projects as assigned.


  • Minimum Qualifications
    • High school graduation or equivalent.
    • Meets basic standards and qualifications for laboratory testing personnel under Clinical Laboratory Improvement Amendments (CLIA), Subpart M, Section 493.1489.

    The CLIA reference can be found at the following website address. This is a direct link: https://www.cms.gov/Regulations-and-Guidance/Guidance/Manuals/downloads/som107ap_c_lab.pdf

    Note: IDPH link to required Laboratory Personnel Qualifications can be found at https://dph.illinois.gov/content/dam/soi/en/web/idph/files/publications/clia-laboratorypersonnelqualifications.pdf

    Note: It is recommended that, in order to ensure consistent application of these qualifications, the evaluation and verification of an applicant's credentials be accomplished through the cooperative efforts of an experienced clinical laboratory technologist and the personnel department in a manner which will preserve the applicant's anonymity.

    Preferred Qualifications
    • A minimum of 1-2 years of experience in related field
    • Must have a bachelor's degree (BA or BS) in Science, that meets the CLIA requirements to perform high complexity testing.
    • Possesses and applies comprehensive knowledge of research principles, concepts, practices and methods
    • Experience in working with different widely used sequencing platforms and genomic analysis pipelines preferred
    • Experience with programming using UNIX/LINUX clusters preferred
    • Proficiency with Microsoft Excel, Word, and PowerPoint
    • Understand and follow the guidelines for prevention of contamination of molecular testing areas.
    • Understand the function of the medical laboratories in the health care environment.

    Certification in one of the following certifications:
    • Certified as Medical Laboratory Scientists, Clinical Laboratory Scientist, Medical Technologist, Histotechnologist (HTL), or categorical (BB, C, CG. CT, DLM, H, M, MB, PA, SCYM) certification by Board of Certification. (ASCP).
    • Certified as a Medical Technologist by American Medical Technologists (AMT)
    • Certified as Clinical Laboratory Scientist by National Credentialing Agency for Laboratory personnel (NCA)
    • Clinical Microbiology registry from American Society for Microbiology, RM(AAM)
    • Certified Histocompatibility Technologist (CHT) by the American Board of Histocompatibility and Immunogenetics (ABHI)


    Fully complete all sections of the online application including adding your full work history with specific details of your duties & responsibilities for each position held. Fully complete the education, licensure, certification, and language sections.

    You may upload a resume, cover letter, certifications, licensures, transcripts, and diplomas within the document section of your online application.

    When completing your online application, please be sure to provide detailed information about your job knowledge and specific duties and responsibilities, as your qualifications for any Civil Service position will be primarily determined based on what is contained in the application. Dates of employment and if employed on a full or part time basis (including number of hours per week) must be indicated for each position held. Additional consideration will be given to supporting documentation i.e., resume, transcripts, licenses, and certifications so please be sure to attach all applicable documents.

    If an application is not fully completed and submitted by the close date, the applicant/employee will not be considered for this position.

    For fullest consideration, the above-mentioned requirements must be submitted no later than 12/2/2024.

    Please note that once you have submitted your application you will not be able to make any changes. In order to revise your application, you must withdraw and reapply. You will not be able to reapply after the posting close date. Please ensure the application is fully completed and all supporting documents have been uploaded before the posting close date.

    This is a full-time and benefits eligible position. UI Health offers competitive salaries commensurate with experience. All full time benefits eligible positions include a comprehensive benefits package which include; Health, Dental, Vision, Life, Disability & AD&D insurance, a defined benefit pension plan as well as paid leave which includes; Vacation, Holiday and Sick. In addition, we offer tuition waivers for employees and dependents. Go to https://www.hr.uillinois.edu/benefits for a complete list of Employee Benefits.

    The University of Illinois System is an equal opportunity employer, including but not limited to disability and/or veteran status, and complies with all applicable state and federal employment mandates. Please visit Required Employment Notices and Posters to view our non-discrimination statement and find additional information about required background checks, sexual harassment/misconduct disclosures, and employment eligibility review through E-Verify.

    The university provides accommodations to applicants and employees. Request an Accommodation
    Looking for more University of Illinois positions?

    We invite you to search for positions at each of the University of Illinois locations, the University of Illinois System Office and the University of Illinois Foundation. The University of Illinois System Office supports the primary missions of teaching, research, public service, and economic development for all of the Universities and offers positions in all locations. The University of Illinois Foundation is the official fundraising and private gift-receiving agency for the University of Illinois and also offers position in all locations. Click the links below to search for other University of Illinois positions.

    University of Illinois Urbana-Champaign
    University of Illinois Springfield
    University of Illinois System Office
    University of Illinois Foundation

    The University of Illinois System is an equal opportunity employer, including but not limited to disability and/or veteran status, and complies with all applicable state and federal employment mandates. Please visit Required Employment Notices and Posters to view our non-discrimination statement and find additional information about required background checks, sexual harassment/misconduct disclosures, and employment eligibility review through E-Verify.

    To apply, visit https://uic.csod.com/ux/ats/careersite/1/home/requisition/12193?c=uic

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