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A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation's top public universities. Known for its beautiful campus, world-class medical care, commitment to the arts and top athletic programs, Carolina is an ideal place to teach, work and learn.

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Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education and research.

Patient care: We promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond.

Education: We prepare tomorrow`s healthcare professionals and biomedical researchers from all backgrounds by facilitating learning within innovative and integrated curricula and team-oriented interprofessional education to ensure a highly skilled workforce.

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The Department of Psychiatry at the University of North Carolina at Chapel Hill School of Medicine is seeking a physician-scientist with strong skills in computational neuroscience, structural biology, and molecular pharmacology to advance precision-medicine approaches in serious mental illness. The Research Assistant Professor position is a full-time, fixed-term appointment at the Research Assistant Professor level. Experience integrating in vitro functional assays (e.g., Bioluminescence Resonance Energy Transfer) with in silico structural methods (e.g., AlphaFold-based structure prediction and molecular dynamics simulations) is required. The successful candidate will develop a research program characterizing how genetic variants of neuroreceptors modulate medication binding and receptor dynamics, with the goal of informing pharmacogenetically guided drug selection in schizophrenia and other neuropsychiatric disorders. Additionally, the successful candidate is expected to be a skilled, independent researcher with excellent experience in designing and executing research studies, mentoring graduate students and other trainees, and writing research papers and grants.

1. MD or equivalent medical degree.
2. Completion of, or near-completion of, residency training in psychiatry or a closely related clinical neuroscience specialty.
3. Research training and demonstrated experience in computational neuroscience, structural biology, and/or molecular pharmacology, including molecular dynamics simulations and/or cell-based functional receptor pharmacology assays.
4. Strong peer-reviewed publication record in computational, structural, and/or molecular neuroscience.

1. PhD or MD/PhD in neuroscience, computational neuroscience, bioengineering, structural biology, or a related quantitative discipline.
2. Experience with G protein-coupled receptor ( GPCR) structural biology, AlphaFold-based protein structure prediction, and high-performance computing for large-scale molecular dynamics simulations.
3. Experience with Bioluminescence Resonance Energy Transfer ( BRET) or comparable cell-based functional assays, and a track record of competitive extramural research funding.
4. Ability to coordinate multi-disciplinary studies with collaborators from diverse scientific backgrounds.

If you experience any problems accessing the system or have questions about the application process, please contact the University's Executive Vice Chancellor and Provost office at (919)-962-1091 or send an email to facultyrecruitment@unc.edu.

Please note: The Executive Vice Chancellor & Provost office will not be able to provide specific updates regarding position or application status.

If you have any questions about the job requirements or the hiring department notify the Department Contact.

The University is an equal opportunity employer and welcomes all to apply without regard to age, color, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, or sexual orientation. We encourage all qualified applicants to apply, including protected veterans and individuals with disabilities.