Research Lab Tech I RESEARCH NEUROLOGY HV
 Brigham and Women's Hospital | |
 United States, Massachusetts, Boston | |
| 60 Fenwood Road (Show on map) | |
 Apr 21, 2026 | |
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Summary
The Venkatesh Lab (www.venkateshlab.org) is seeking a highly motivated lab technician to join our pioneering research efforts in the field of cancer neuroscience. Our lab's exciting new area of research lies at the intersection of cancer biology and neuroscience - we focus on characterizing and therapeutically targeting electrical components of disease pathophysiologies. By improving our understanding of the cellular and molecular mechanisms involved in neuron-cancer communication and circuit formation in and outside of the brain, the Venkatesh Lab aims to harness the systems level microenvironmental dependencies of tumor growth to develop innovative therapeutic treatments. Responsible for maintaining laboratory equipment, organizing and preparing samples, conducting experiments, and recording and analyzing data. Does this position require Patient Care? No. Essential Functions -Perform laboratory experiments following established protocols and procedures. -Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines. -Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed. -Record experimental data accurately and maintain organized records of procedures, protocols, and results. -Compile and analyze data using appropriate statistical and analytical methods. -Assist in data interpretation and presentation, contributing to research findings and reports. Education Research Support - 70% -Operate specialized instruments such as sliding microtomes, vibrotomes, and cryostats to prepare tissue sections for various organs. -Perform routine cell culture techniques, including cell passage, freezing, and thawing. -Analyze and quantify microscopy results to support project goals and reporting. -Troubleshoot and preform molecular biology techniques such as virus production, primer design, molecular cloning, and transfection. -Perform techniques such as Western blotting, viral transduction, next-generation sequencing (NGS). -Assist in microscopy imaging, including confocal and fluorescence microscopy. -Learn, master, and implement surgical techniques commonly used in preclinical models. -Optimize and troubleshoot immunofluorescence, immunohistochemistry, and in situ hybridization protocols. Mouse Husbandry - 20% -Responsible for the maintenance and care of laboratory mice including breeding, weaning, ear tagging, and allocation to lab members. -Maintain up to date mouse records and reports on mouse census to supervisors. -Necropsy and tissue harvesting from various mouse models. Lab Upkeep - 10% -Maintain a clean and well-organized work environment, ensuring proper storage of reagents, cells, and samples. -Manage laboratory inventories, including ordering reagents and maintaining stock levels of commonly used consumables. -Receive, store, and document reagents/packages -Assist in ensuring compliance with institutional biosafety, animal care, and chemical safety regulations. -Help maintain accurate lab documentation, including protocols, experimental records, and safety data sheets. Qualifications: -Bachelor's degree in biology or related life sciences major. 1-2 years of experience outside of coursework required. -Demonstrated experience with tissue culture and aseptic technique. -Experience with rodent handling, husbandry, and animal experiments. -Must have demonstrated experience in molecular techniques, particularly cloning and transfection. -Ability to design, execute, and troubleshoot protocols and experiments for various projects in the lab. -Must be able to maintain detailed and accurate laboratory notebooks documenting experimental procedures, results, and observations. -Compile, analyze, and present data in a timely fashion. The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. | |