Scientist I - Functional Genomics | Muscle Biology

Make your mark for patients

UCB Biosciences is seeking to hire an exceptional Scientist I - Functional Genomics & Muscle Biology to join our Genomics and Integrative Biology Group located in Durham, NC. This is an office-based position with the expectation of being in the lab 5 days a week. The role contributes at an in vitro technical level to design studies, produce and interpret data, and contribute to current and future drug discovery projects. Skills should include molecular and cell biology knowledge together with previous experience of a range of in vitro-based technology capabilities and screening approaches. Previous experience in working with muscle cells and/or neuromuscular diseases is a requirement.

Primary responsibilities:

• Design and execution of functional genomics assays/screens to identify and validate novel targets including assessment of relevant biology in screening models, and validation of hits
• Development of novel in vitro assays for functional genomics screens
• Develop cell models for muscle disease modeling that can be used with functional genomics assay
• Provide scientific insight into projects in consultation with UCB on functional genomics (medicinal chemists, cell biologists, disease area experts, antibody engineers, etc.)
• Provide strong scientific thinking, develop hypotheses and drive scientific learnings on projects/functional genomics platform
• Time split between 80:20 between wet lab and office responsibilities

Required Education and Experience:

• Master's degree with 3 to 6 years of experience or PhD with 0 to 2 years of experience in applicable field with record of scientific achievement as evidenced by publications, presentations, or patents
• Experience in applying cellular and biochemical techniques for target identification, validation, genetic screening and evaluating the mechanism of action of novel molecular entities
• Experience in molecular biology approaches and advanced cell biology techniques (flow cytometry, gene and protein analysis, PCR, cloning, lentiviral library prep)
• Excellent communicator, with demonstrated ability to work across disciplines
• Ability to work independently and manage priorities and engage in a multidisciplinary environment

Preferred experience:

• Experience in single cell analysis
• Experience in in vivo models for Neuromuscular Disorders

Base Salary Range: $88,000 to $115,500

Are you ready to 'go beyond' to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!

About us
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are over 9.000 people in all four corners of the globe, inspired by patients and driven by science.

Why work with us?
At UCB, we don't just complete tasks, we create value. We aren't afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equal opportunities to do their best work. We 'go beyond' to create value for our patients, and always with a human focus, whether that's on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.

At UCB, we've embraced a hybrid-first approach to work, bringing teams together in local hubs to foster collaborative curiosity. Unless explicitly stated in the description or precluded by the nature of the position, roles are hybrid with 40% of your time spent in the office.

UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable federal, state, or local law. UCB invites you to voluntarily self-identify during the application process. Provision of self-identification information is entirely voluntary and a decision to provide or not provide such information will not have any effect on your application for employment, your employment with UCB, or otherwise subject you to any adverse treatment. Any information you provide will be considered confidential and will be kept separate from your application and/or personnel file and will only be used in accordance with applicable laws, orders, and regulations.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on US-Reasonable_Accommodation@ucb.com for application to US based roles. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.