O'Connor Lab Research Specialist

We are seeking a Research Specialist to join our expanding environmental surveillance team. The position involves processing air samples and clinical nasal swab samples collected at various locations within the local community as well as other domestic and international sites that are expanding their air sample collection. We have many ongoing projects, but our overarching goal is to use air sampling to monitor for common and emerging respiratory illnesses. The successful candidate will work under the supervision of the principal investigators and senior lab scientists, as well as with a team of undergraduate researchers and research specialists. Nucleic acids from the collected samples are isolated then are assayed to determine which respiratory pathogens are present using multiplex PCR panels and metagenomics assays. In some weeks, the candidate will also be responsible to drive to pick up air samples in a University fleet vehicle so a valid driver's license with a clean driving record is required. In the laboratory, you will process air samples and nasal swab samples for nucleic acid extraction and perform multiplex PCR assays. You will also perform routine laboratory maintenance and quality control procedures to ensure data integrity and equipment functionality. These technical responsibilities require attention to detail and adherence to established protocols for sample handling and processing. Other duties will include helping to design and execute quality control experiments and optimizing novel PCR assays to expand our ability to detect a greater number of pathogens.

Other research support duties will involve assisting in sample management and inventory, data analysis and preparation for publication, contributing to ongoing research projects as needed, and maintaining detailed records and documentation. This aspect of the role provides exposure to the full research pipeline from sample collection through scientific publication. Applicants that have worked in a research laboratory setting with strong molecular biology skills and wet lab bench experience are encouraged to apply. Specifically, we are seeking applicants who have experience performing RNA and DNA isolation (both automated and manual methods), optimization/troubleshooting for PCR/RT-PCR/digital PCR assays, high throughput sample processing, and/or using microfluidics sample processing platforms. In addition, since management of large numbers of samples and interpretation of sequencing data are complex, the successful applicant needs to have strong organizational and data analysis/computer skills.

• This position requires work to be completed onsite, at a designated campus work location.

• Must provide a valid driver's license. Employees may use their own transportation or receive approval for University Car Fleet usage. Employment is conditional pending the results of a Pre-hire Driver Authorization Check. See https://businessservices.wisc.edu/managing-risk/driver-authorization-and-insurance/driver-authorization/#become-authorized-driver (click on "Become an authorized driver;" then click on "Required criteria").

• Reviews, analyzes, and interprets data and/or documents results for presentations and/or reporting to internal and external audiences

• Performs literature reviews and writes reports

• Operates, cleans, and maintains organization of research equipment and research area. Tracks inventory levels and places replenishment orders

• Conducts research experiments according to established research protocols with moderate impact to the project(s). Collects data and monitors test results

• Provides operational guidance on day-to-day activities of unit or program staff and/or student workers

• Participates in the development, interpretation, and implementation of research methodology and materials

School of Medicine and Public Health, Department of Pathology & Laboratory Medicine, O'Connor Lab

The Department of Pathology and Laboratory Medicine is dedicated to the highest quality patient care, cutting-edge and impactful research, and teaching the next generation of pathologists and scientists. We emphasize a healthy work-life balance and provide a supportive work environment committed to the growth and advancement of our members. Our vibrant clinical department integrates anatomic pathology, laboratory medicine, teaching, and a robust research enterprise, and serves the UW, American Family Children's, VA, and other Madison hospitals. Our basic science and translational research programs have made fundamental discoveries in cell and stem cell biology, immunology, neuroscience, and infectious disease. Opportunities in education include a T32-funded PhD graduate program, pathology resident and fellowship programs, and both medical school and undergraduate curricula.

Madison, often rated as one of the best places to live in America, is built on an isthmus, surrounded by lakes. The city, campus, green spaces and urban areas are blended to create a place unlike any other.

The starting salary for the position is $44,543 annually; but is negotiable based on experience and qualifications.

Employees in this position can expect to receive benefits such as generous vacation, holidays, and sick leave; competitive insurances and savings accounts; retirement benefits. For more information, refer to the campus benefits webpage. SMPH Faculty /Academic Staff Benefits Flyer 2026

• Experience in designing and conducting experiments.

• Experience in data collection and analysis.

• Experience with written and verbal scientific communication.

Bachelor's Degree preferred; focus in public health, immunology, microbiology, virology, or a related field is preferred.

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University sponsorship is not available for this position, including transfers of sponsorship and TN visas. The selected applicant will be responsible for ensuring their continuous eligibility to work in the United States (i.e. a citizen or national of the United States, a lawful permanent resident, a foreign national authorized to work in the United States without the need of an employer sponsorship) on or before the effective date of appointment. This position is an ongoing position that will require continuous work eligibility. If you are selected for this position you must provide proof of work authorization and eligibility to work.

Tia Seguin, tia.seguin@wisc.edu, 608-263-3731

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