Analytical Chemistry - Postdoctoral Researcher

Join us and make YOUR mark on the World!

Are you interested in joining some of the brightest talent in the world to strengthen the United States' security? Come join Lawrence Livermore National Laboratory (LLNL) where our employees apply their expertise to create solutions for BIG ideas that make our world a better place.

We are dedicated to fostering a culture that values individuals, talents, partnerships, ideas, experiences, and different perspectives, recognizing their importance to the continued success of the Laboratory's mission.

Pay Range

$118,884 Annually

We are seeking a highly motivated Analytical Chemistry Postdoctoral Researcher to join our dynamic team and play a key role in pushing the boundaries of analytical chemistry with advanced LC-MS techniques. Tackle complex analytical challenges using state-of-the-art instrumentation and innovative approaches. Lead method development for both targeted and untargeted analyses, apply high-resolution mass spectrometry for structural elucidation, and contribute to research projects with significant real-world impact.

As part of our multidisciplinary group, you will collaborate with experts in chemistry, biology, and forensic science, leveraging your LC-MS expertise to address research needs of national security importance. Your work will directly support unique federal law enforcement efforts performing forensic analysis and conducting critical R&D with high-impact consequences. This position offers hands-on experience with groundbreaking technologies, providing a platform for publishing your discoveries, and opportunities to expand your expertise in small molecule and proteomic analyses. The role is based in the Forensic Sciences and Assessment Group of the Nuclear and Chemical Sciences Division, within the Physical and Life Sciences Directorate and is matrixed to LLNL's Forensic Science Center, a national security asset with expertise in state-of-the-art analytical forensic chemistry.

This position requires full-time on-site presence due to the nature of the work.

You will

• Exploit diverse real-world samples by unraveling the molecular composition and forensic meaning of complex, unknown materials using high-resolution mass spectrometry and advanced data analytics.
• Drive innovation by collaborating with scientists, planning experimental campaigns, and coordinating resources to deliver breakthrough research outcomes.
• Research, design, and execute targeted and untargeted chemical analyses across a wide range of analytes.
• Pursue independent, complementary research interests including writing prospective proposals, engaging with a broad network of scientists within and outside the laboratory.
• Develop research plans, interpret results, and communicate findings through peer-reviewed publications, technical reports, and presentations for internal and external audiences, including sponsors, stakeholders, and scientific conferences.
• Operate, maintain, and troubleshoot analytical instrumentation (HPLC/UHPLC, LC-MS, and associated detection technologies).
• Maintain detailed and accurate laboratory notebooks, documenting all processes and procedures, and ensure compliance with ethical, institutional, regulatory, and safety policies.
• Perform additional duties as assigned.

• Ability to obtain and maintain a U.S. Department of Energy Q-level security clearance (U.S. Citizenship required).
• PhD in Chemistry, Biology, Forensic Science, or a related field.
• Experience with applied organic mass spectrometry, particularly in developing and utilizing LC-MS methods, including high-resolution mass spectrometry (e.g., Orbitrap or TOF) and MS/MS techniques.
• Familiarity with complimentary spectrometric techniques (e.g., GC-MS) and analytical methodologies (NMR, IR, UV).
• Advanced organization and time-management skills, with adaptability to dynamic research priorities and the ability to multi-task and meet deadlines.
• Proven ability to work independently and collaboratively within multidisciplinary teams.
• Excellent verbal, written, and interpersonal communication skills for effective interaction with scientists, engineers, and technical/administrative staff.
• Demonstrated ability to conduct independent research, as evidenced by peer-reviewed publications.

Qualifications We Desire

• Experience with forensic laboratory operations, including ISO17025 quality management requirements.
• Advanced skills in chromatographic separations, LC-MS method optimization, and application to diverse molecular classes (small molecules, peptides, proteins).
• Experience with untargeted analysis to identify small molecules, peptides, and proteins of interest, including de novo proteomics.
• Demonstrated success in presenting and publishing research to broad scientific and stakeholder audiences.
• Familiarity with data analysis workflows, chemometrics, or bioinformatics relevant to analytical chemistry.

#LI-Onsite

Position Information

This is a Postdoctoral appointment with the possibility of extension to a maximum of three years, open to those who have been awarded a PhD at time of hire date.

Why Lawrence Livermore National Laboratory?

• Included in 2025 Best Places to Work by Glassdoor!
• FlexibleBenefits Package
• 401(k)
• Relocation Assistance
• Education Reimbursement Program
• Flexible schedules (*depending on project needs)
• Our values - visithttps://www.llnl.gov/inclusion/our-values

Security Clearance

This position requires a Department of Energy (DOE) Q-level clearance.If you are selected, wewill initiate a Federal background investigation to determine if youmeet eligibility requirements for access to classified information or matter. Also, all L or Q cleared employees are subject to random drug testing. Q-level clearance requires U.S. citizenship.

Pre-Employment Drug Test

External applicant(s) selected for this position must pass a post-offer, pre-employment drug test. This includes testing for use of marijuana as Federal Law applies to us as a Federal Contractor.

Wireless and Medical Devices

Per the Department of Energy (DOE), Lawrence Livermore National Laboratory must meet certain restrictions with the useand/or possession ofmobile devices in Limited Areas. Depending on your job duties, you may be required to work in a Limited Area whereyou are not permitted to have a personal and/or laboratory mobile devicein your possession. This includes, but not limited to cell phones, tablets, fitness devices, wireless headphones, and other Bluetooth/wireless enabled devices.

Ifyou useamedical device, whichpairs with a mobile device,you must still follow the rules concerningthe mobile device in individual sections within Limited Areas. Sensitive Compartmented Information Facilities requireseparate approval. Hearing aids without wireless capabilities or wireless that has been disabled are allowed in Limited Areas, Secure Space and Transit/Buffer Space within buildings.

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We are an equal opportunity employer that is committed to providing all with a work environment free of discrimination and harassment. All qualified applicants will receive consideration for employment without regard to race, color, religion, marital status, national origin, ancestry, sex, sexual orientation, gender identity, disability, medical condition, pregnancy, protected veteran status, age, citizenship, or any other characteristic protected by applicable laws.

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