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The Position
The Opportunity The Head of US Medical Population Science & Health (USM PS&H) will lead the CMG US Medical Population Science & Health team reporting to the VP Head of US Medical. This role is part of the US Medical Leadership Team, alongside other senior leaders such as the VP, Head of Scientific Operations. This individual will manage a team of two Medical Science Health Population Directors, and one Field Medical Health Population Director , focused on advancing population science and health outcomes for all Genentech and Roche patients and aligned with specific therapy area initiatives. They will ensure long-term, sustainable above-brand PS&H strategies that support Roche's 2030 vision. The Head of USM PS&H will collaborate with other USM teams and functional leads to ensure enterprise-wide strategic alignment, acting as a key medical spokesperson internally and externally with various committees, regulatory bodies, and industry forums. This individual will represent USM across the enterprise, engaging with executive teams from PD, gRED, pRED, and CMG, serving on the USLT and ecosystem leadership teams, and maintaining global alignment. . Externally, they will be the primary USMA PS&H contact for C-suite healthcare professionals, while their team will focus on engagements with the Field and Medical Network.. Key Responsibilities Strategic Leadership & Vision
Build sustainable Population Science & Health (PS&H) strategies aligned with CMG and Roche 2030 visions, ensuring alignment with Squads and Medical teams. Integrate PS&H into USM strategy and field medical execution through playbooks, frameworks, and training. Embed Population Science and Health across the Medical organization, leading strategy and efforts, and translating enterprise vision into cross-portfolio clinical and evidence generation plans. Lead interactions with regulatory agencies and experts, partnering with Squads to develop and communicate integrated PS&H strategies.
Operational & Financial Accountability
Responsible for budget management of PS&H activities in USMA, delivering Phase IIIb/IV studies, and strengthening Genentech's ability to execute clinical trials, especially for specific populations, to reduce trial delays or non-approvals. Drives evidence generation and trial outcomes by providing U.S.-specific data for regulatory approvals, payer negotiations, and inclusive research standards, aiming for faster clinical trial enrollment and increased participation from underrepresented communities; may also serve as Medical Monitor back-up and embed best practices for broader patient representation in trials.
Cross-Enterprise Representation & Collaboration
Represent USMA PS&H internally, interfacing with executive leadership teams (PD, gRED, pRED, CMG), and externally, representing USMA PS&H at USM and PH CoE leadership meetings. Proactively guide Field Medical and USM engagement with underserved health systems and clinicians to expedite recruitment and successful completion of critical Phase IV trials. Lead across the One Roche Enterprise, engaging with C-Suite Executives from Foundation Medicine, Flatiron, and Roche Diagnostics.
Field Population Health Support Oversight
Provide strategic direction and guidance for the Medical Science Health Population Directors and Field Medical Health Population Director , ensuring alignment with national objectives and equitable health outcomes by strengthening partnerships with underserved health systems, community providers, and ecosystem stakeholders, and equipping field medical teams to communicate PS&H value, build trust, strengthen trial site relationships, and support patient enrollment, while also ensuring consistent bi-directional knowledge flow between field team insights and internal strategy to optimize PS&H impact and responsiveness.
Compliance, Risk & Governance
Ensure the PSH team follows compliance governance practices and processes relevant to collaborative work (e.g., confidentiality, intellectual property, data privacy, interactions with customers, pharmacovigilance) and proactively manage risk in external collaborations and evidence generation, ensuring alignment with Roche standards, legal frameworks, and evolving global regulatory expectations.
External Partnerships & Community Impact
Lead strategic partnerships and serve as a senior medical spokesperson to advance population science and health. This includes collaborating with national payers and healthcare institutions to improve access to Roche medicines for underserved patients, promoting PS&H's vision with KOLs, regulators, and executives, and enhancing Genentech's reputation in population health to strengthen external partnerships. Drive initiatives to educate underserved communities. Partner with the Population Health CoE on novel internal or external initiatives to address knowledge and trust gaps among providers, investigators, and patients in underserved communities.
Team Culture & Organizational Influence
Champion a high-performing environment within the PS&H team that fosters accountability, innovation, and collaborative ways of working across functions, while also co-creating an inspiring team culture by consistently living the Genentech Operating Principles and fostering an environment of respect and collaboration.
Who you are Qualifications & Experience
Advanced degree (MD, PhD, PharmD) in MPH or other relevant field. 15+ years of pharmaceutical or biotechnology industry experience, or 10+ years, including at least 5 years in Medical Affairs or Clinical Development leadership roles.
Deep expertise in population health, real-world data, and upstream interventions. Track record of strategic influence, organizational change leadership, and enterprise collaboration, including engaging senior external stakeholders and representing organizations at national forums. Demonstrated experience supervising and developing high-performing teams, including in-house and field-based medical professionals. Significant experience operating effectively and delivering results with a strong focus on compliance and integrity, along with an understanding of Phase I-III and/or Phase IV drug development.
Preferred Qualifications & Experience
MPH or other population health-related training. Possess a sophisticated understanding of the evolving global and US regulatory, medical practice, and economic environments impacting Roche/Genentech, coupled with thorough knowledge of US regulatory/FDA requirements. Scientific credibility and enterprise thinking on how Medical Affairs impacts the broader organization, with ability to provide proactive solutions to complex needs. Understanding of legal and regulatory considerations impacting the pharma/biotech industry, and ability to apply these principles effectively to daily activities.
Travel Requirements The position is located in South San Francisco. The position may require up to 25% time traveling. The expected salary range for this position based on the primary location of South San Francisco, CA is $269,700 - 500,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits Relocation benefits are not available for this job posting. Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
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Genentech
Sep 25, 2025