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Postdoctoral Fellow

Institute for Systems Biology
United States, Washington, Seattle
401 Terry Avenue North (Show on map)
May 12, 2025

The Hadlock lab at the Institute for Systems Biology (ISB) in Seattle, WA is seeking a Postdoctoral Fellow to join our interdisciplinary team, advancing translational research in systems biology. Our lab focuses on two areas of investigation: biomedical modeling to inform clinical decisions and research priorities, and 2) developing new data science approaches to accelerate discovery. We work with high-fidelity data from prospective studies that combine deep phenotype and exposure data, ranging from genomics/multiomics to health-related social needs and other geospatial data. We also have access to one of the largest collections of comprehensive electronic health records in the world, with longitudinal data for over 31,000,000 patient records from 51 hospitals and 1085 clinics across seven states. Our team collaborates with systems biologists, data scientists, and physicians across the country. Current projects include analysis of immune-mediated inflammatory disease, placental transcriptomics, and modeling T-cell receptor repertoires in post-acute sequelae of infectious disease. Our lab acts as a catalyst for high-impact projects, and we offer the data, tools, support and flexibility needed for fellows to make rapid progress on novel research. This one-year position offers significant opportunities for growth and career advancement.

Responsibilities include:



  • Developing, validating and interpreting rigorous models to gain insight into new onset of disease
  • Multimodal machine learning with longitudinal genotype, phenotype and exposome data
  • Developing or applying machine learning and/or biostatistics to detect patterns that can improve clinical decision support and accelerate biomedical discovery
  • Submitting results for publication
  • Participating on collaborative research projects with colleagues at ISB and nationwide



Qualifications:



  • Applicants should hold (or shortly be awarded) a PhD in Bioinformatics, Computational Biology, Mathematics, Statistics, Data Science or a related field.
  • Published, peer-reviewed articles
  • Expertise machine learning and bioinformatics
  • Experience working with single cell data
  • Python, R, or experience learning new multiple coding languages
  • Ability to work effectively with people in an interdisciplinary workforce


Preferred candidates will also have at least one of the following:



  • Analysis of single cell data
  • Developing or evaluating new methods for modeling and analysis
  • Integrating knowledge into from databases, trees, graphs, ontologies or free text



Interested applicants will be considered for the Lee Hood Systems Fellows Program.

https://isbscience.org/careers/postdocs

https://isbscience.org/careers/postdocs/hood-fellows/

Applicants should include a CV and a brief cover letter to be considered for this position.

Two references will be required prior to starting work.

Benefits: https://isbscience.org/careers/benefit-summary/

Pay Range: Postdoctoral Fellows are paid depending on years of experience in the range of $77,969 - 95,787

ISB is an equal opportunity employer.

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