Research Scientist I

The Hadlock lab at the Institute for Systems Biology (ISB) in Seattle, WA is seeking a Research Scientist to join our interdisciplinary team, advancing translational research in systems biology. Our lab focuses on two areas of investigation: biomedical modeling to inform clinical decisions and research priorities, and 2) developing new data science approaches to accelerate discovery. We work with high-fidelity data from prospective studies that combine deep phenotype and exposure data, ranging from genomics/multiomics to health-related social needs and other geospatial data. We also have access to one of the largest collections of comprehensive electronic health records in the world, with longitudinal data for over 31,000,000 patient records from 51 hospitals and 1085 clinics across seven states. Our team collaborates with systems biologists, data scientists, and physicians across the country. Current projects include analysis of immune-mediated inflammatory disease, placental transcriptomics, and modeling T-cell receptor repertoires in post-acute sequelae of infectious disease. Our lab acts as a catalyst for high-impact projects, and we offer the data, tools, support and flexibility needed for fellows to make rapid progress on novel research. This one-year position offers significant opportunities for growth and career advancement.

Responsibilities include:

• Developing, validating and interpreting rigorous models to gain insight into new onset of disease
• Multimodal machine learning with longitudinal genotype, phenotype and exposome data
• Developing or applying machine learning and/or biostatistics to detect patterns that can improve clinical decision support and accelerate biomedical discovery
• Submitting results for publication
• Contributing to new research proposals
• Coordinating collaborative research projects with colleagues at ISB and nationwide
  

Qualifications:

• PhD in Bioinformatics, Computational Biology, Mathematics, Statistics, Data Science or comparable knowledge and skills from work experience
• Published, peer-reviewed articles
• Expertise machine learning and bioinformatics
• Experience working with single cell data
• Python, R, or experience learning multiple new coding languages
• Excellent organizational and communications skills, including knowledge of collaborative applications and tools
• Ability to work effectively with people in an interdisciplinary workforce, adapt to changing work requirements, and prioritize across multiple concurrent projects

Preferred candidates will also have experience with one or more of the following:

• Integrating knowledge into from databases, trees, graphs, ontologies or free text
• Developing or evaluating new methods for modeling and analysis
• Leading projects
  

Applicants should include a CV and a brief cover letter to be considered for this position.

Two references will be required prior to starting work.

Benefits: https://isbscience.org/careers/benefit-summary/

Pay Range: $77,969 - 104,680

ISB is an equal opportunity employer.