Hourly Research Scientist (Internship)

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Responsibilities

Health Research, Inc. is seeking an Hourly Research Scientist to work within the Division of Translational Medicine at the Wadsworth Center of the New York State Department of Health to assist in the implementation of a novel purification method to isolate ribosomes from small volumes of cell culture. Ribosomes are protein-synthesizing molecular machinery that are a primary target of antibiotics used to treat bacterial diseases. Recently, a technique called RAPPL (RNA Affinity Purification using Poly-Lysine) has been developed as a simple, cost-effective, and rapid method to purify active ribosomes from small cell culture volumes. The incumbent will assist in optimizing this method for purifying ribosomes from Escherichia coli (Eco) cell cultures, assess its efficacy of purification to previous ribosome purification methods such as sucrose fractionation, and then apply it to purify ribosomes from other cell cultures, such as Mycobacterium smegmatis (Msm). The work may involve activities including but not limited to ordering supplies, buffer preparation, bacterial cell culture, ultra-centrifugation, sucrose fractionation, RNA gel separation, protein gel separation, cryo-electron electron microscopy grid preparation, and related biochemical assays. This is a great opportunity to learn cutting-edge techniques used in scientific research that is geared towards solving major public health issues.

This position is part of the Pathways to Public Health Internship Program. This position will last approximately 10 weeks from 6/2/2025 to 8/8/2025. It is made available through funding from the Center for Disease Control's Public Health Infrastructure Grant to expand opportunities to strengthen career pathways to public health by bringing together students of all disciplines and academic levels with public health professionals to create a space of exploration, learning, and development.

Minimum Qualifications

Bachelor's degree in biochemistry, biology, chemistry.

• Experience in performing protein purification, biochemical assays or similar procedures in a laboratory or clinical setting.

• Experience reviewing scientific literature.

• Experience writing reports and providing presentations.

Conditions of Employment
Hourly, grant funded position expected to last through 08/8/2025. Compliance with funding requirements such as time and effort reporting, grant deliverables, and contract deliverables, is required.

Valid and unrestricted authorization to work in the U.S. is required. Visa sponsorship is not available for this position.

Travel, up to 10% of the time, will be required.

The selected candidate must reside within a reasonable commuting distance of the official work location specified in the job posting and must also be located in or willing to relocate to one of the following states: New York, New Jersey, Connecticut, Vermont, or Massachusetts, prior to hire. Telecommuting will be available.

HRI participates in the E-Verify Program.

HRI embraces diversity, equity, and inclusion in our workforce. This is reflected in our affirmative action equal employment opportunity policy.

Affirmative Action/Equal Opportunity Employer/Qualified Individuals with Disabilities/Qualified Protected Veterans

www.healthresearch.org

About Health Research, Inc.

Join us in our mission to make a difference in public health and advance scientific research! At Health Research, Inc. (HRI), your work will contribute to meaningful change and innovation in the communities we serve! At HRI, we are on a mission to transform the health and well-being of the people of New York State through innovative partnerships and cutting-edge public health initiatives. As a dynamic non-profit organization, HRIplays a crucial role in advancing the strategic goals of the New York State Department of Health (DOH), Roswell Park Comprehensive Cancer Center (RPCCC), and other health-related entities.