Staff Research Associate

Microbiology and Immunology

Full Time

84439BR

Job Summary

The Staff Research Associate engages in extensive in vitro and in vivo studies of next generation T cell therapies for solid tumors. These studies will include molecular biology (cloning), gene-editing and viral and non-viral transduction of T cells, cell culture, engineered T cell activity (CAR T, TCR T etc) assays (cytotoxicity, proliferation, cell phenotype assessment via flow), in vivo assessment of cell therapies in xenograft and syngeneic settings and general lab support to maintain critical reagents. In vivo work will include tail vein injections of engineered T cells and subcutaneous or intraperitoneal injections of tumor cells into NSG mice or immuncompetent mice (syngeneic mouse tumor models). For all studies, tumor growth will be assessed via bioluminescence or caliper. T cells and tumor cells will also be collected from peripheral blood, tissue, and tumor samples to analyze cell numbers and phenotyping will be performed via flow cytometry and next-generation sequencing.

The final salary and offer components are subject to additional approvals based on UC policy.

Your placement within the salary range is dependent on a number of factors including your work experience and internal equity within this position classification at UCSF. For positions that are represented by a labor union, placement within the salary range will be guided by the rules in the collective bargaining agreement.

The salary range for this position is $28.04 - $45.09 (Hourly Rate).

To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html

Department Description

The Department of Microbiology & Immunology is a basic science department within the School of Medicine (SOM). We perform scientific research and training. ROYBAL LAB / MICROBIOLOGY & IMMUNOLOGY In the Roybal Lab, we harness the tools of synthetic and chemical biology to enhance the therapeutic potential of engineered immune cells. We take a comprehensive approach to cellular engineering by developing new synthetic receptors, signal transduction cascades, and cellular response programs to enhance the safety and effectiveness of adoptive cell therapies.

Required Qualifications

• BA/BS in a related science and one or more years of recent, directly related work experience following degree completion, utilizing the techniques or methods required by the position; and/or an equivalent combination of education and experience
• Demonstrated ability to work in a team
• Communication and organizational skills
• Excellent demonstrated record of attendance and punctuality
• Accuracy and attention to details
• Independence and initiative in problem solving
• Ability to adhere to all campus safety policies
• Ability to multi task effectively
• Analytical skills
• Experience with cell culture, molecular and biochemistry assays including cloning, PCR, flow cytometry, ELISA, incucyte. In vivo mouse work including tumor measurements and subcutaneous injections.

Preferred Qualifications

• Experience with in vivo mouse work including tail veil, retro-orbital and intraperitoneal injections

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu

Join us to find a rewarding career contributing to improving healthcare worldwide.

Equal Employment Opportunity

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

Organization

Campus

Job Code and Payroll Title

009617 SRA 2 NEX

Job Category

Research and Scientific

Bargaining Unit

University Professional Technical Employees - Research Support Professionals Unit (UPTE-RX)

Employee Class

Career

Percentage

100%

Location

San Francisco, CA

Campus

Parnassus Heights (SF)

Work Style

Fully On-Site

Shift

Days

Shift Length

8 Hours