Researcher

Join a Dynamic Team at the Thoracic Oncology Research Collaborative Hub (TORCH) in the Burns laboratory.

Position Overview: The lab of Dr. Burns is seeking highly motivated individual to join his lab as a Researcher focused on targeted therapies and brain metastases in lung cancer. Extensive experience in cancer biology, in vivo studies (mouse), and molecular biology techniques is necessary with experience in metastases and/or metabolism preferred. This position will oversee two projects aiming to find novel targeted therapies for oncogene driven lung cancer and the treatment of brain metastases. Projects will focus on (1) Development of targeted therapeutic strategies for oncogene driven NSCLC through targeting EMT transcription factors and/or (2) Targeting lung cancer brain metastases through inhibition of the HGF/MET/TWIST1 pathway and metabolic dependencies. Studies will be conducted through the use of in vitro, ex vivo and in vivo systems as well as with patient samples.

Opportunities for Employees: We are committed to supporting employees in continuing their passions and advancing their educational and career goals. Employees are highly encouraged to pursue their own projects and apply for grants, including Pelotonia.

Motivated Individuals: We seek driven individuals who thrive in a team setting and who are passionate about supporting our mission to understand lung cancer mechanisms and develop innovative treatments.

Our Mission: Our mission is simple yet profound: end cancer. We aim to improve and extend the quality of life for lung cancer patients worldwide.

Responsibilities:

• Perform molecular biology techniques, ex vivo and in vivo (mouse) studies to develop targeted approaches to overcome resistance to targeted therapies in oncogene driven lung cancer and develop targeted approaches for the treatment of brain metastases. With the goal of translating these finding to clinical trials for NSCLC.
• Trains junior staff in molecular biology techniques, ex vivo and in vivo (mouse) studies.
• Documents, analyzes and interprets data for presentations, manuscripts, grant requirements (current or new), etc.
• Participates in TORCH lab meetings, journal clubs and other relevant university oncology or immunotherapy meetings.
• Prepares and presents at professional conferences, as well as attending to expand on knowledge base and potential collaborations.

Education and Experience:

• A masters degree in a biological sciences field is required; cancer biology and/or metabolism preferred with at least 6 years experience working in the field, 7+ years preferred.
• Experience in molecular biology techniques and in vivo work with mouse models is required
• Requires successful completion of a background check; qualified candidates may be asked to complete a pre-employment physical including a drug screen.

Desired Experience (Preferred but not Required):

• 8+ years of laboratory experience in cancer biology and/or cell signaling/metabolism after masters degree preferred .

Commitment and Teamwork:

• A strong willingness to work in a team environment is essential.
  • Contribute to TORCH with both expertise and insight into development of collaborative projects, improving upon and troubleshooting current projects.

Function: Research and Scholarship

Subfunction: Research

Career Band: Individual Contributor - Specialized

Career Level: S3

The Ohio State University is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world. The Ohio State University is one of the nations largest and most comprehensive public universities and a top employer in Ohio.

As one of only 54 designated comprehensive cancer centers in the nation, The Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute is dedicated to the creation of knowledge in laboratory, clinical and population-based cancer research. We apply those discoveries to develop more effective approaches to cancer prevention, diagnosis, and therapies providing tomorrows standard of care today. A Cancer-Free World Begins Here.

The OSUCCC James is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nations largest public universities. is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nations largest public universities.

Final Note: We strive to end cancer while enhancing and prolonging the lives of lung cancer patients.