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Postdoc Research Associate - College of Pharmacy - Pharmaceutical Sciences - Thomas Lab

University of Illinois Chicago
United States, Illinois, Chicago
Jan 16, 2025


Postdoc Research Associate - College of Pharmacy - Pharmaceutical Sciences - Thomas Lab

Postdoc Research Associate - College of Pharmacy - Pharmaceutical Sciences - Thomas Lab

Hiring Department: Pharmaceutical Sciences

Location: Chicago, IL USA

Requisition ID: 1029004

Posting Close Date: January 31, 2025

Salary: The salary for this position is $61,000

About the University of Illinois Chicago

UIC is among the nation's preeminent urban public research universities, a Carnegie RU/VH research institution, and the largest university in Chicago. UIC serves over 34,000 students, comprising one of the most diverse student bodies in the nation and is designated as a Minority Serving Institution (MSI), an Asian American and Native American Pacific Islander Serving Institution (AANAPSI) and a Hispanic Serving Institution (HSI). Through its 16 colleges, UIC produces nationally and internationally recognized multidisciplinary academic programs in concert with civic, corporate and community partners worldwide, including a full complement of health sciences colleges. By emphasizing cutting-edge and transformational research along with a commitment to the success of all students, UIC embodies the dynamic, vibrant and engaged urban university. Recent "Best Colleges" rankings published by U.S. News & World Report, found UIC climbed up in its rankings among top public schools in the nation and among all national universities. UIC has over 300,000 alumni, and is one of the largest employers in the city of Chicago.

The University of Illinois Chicago offers a very competitive benefits portfolio. Click for a complete list of Employee Benefits.

An NIH-funded Postdoctoral Research Associate position is available in the laboratory of Dr. Douglas Thomas at the University of Illinois Chicago. This position is open immediately to investigate redox-based mechanisms of epigenetic regulation in diseases.

The Thomas Lab focuses on exploring novel mechanisms of epigenetic gene regulation through a combination of biochemistry, cell biology, and genomics approaches. Our research employs both in vitro and in vivo models, integrating advanced methodologies such as mass spectrometry, confocal microscopy, electron paramagnetic resonance imaging of free radicals, chemiluminescence, electrochemical analyses, genomic, and molecular biology techniques.

Notably, we have identified the free radical signaling molecule nitric oxide (NO) as an endogenous regulator of epigenetics, capable of influencing mRNA, histone, and DNA methylation. Current projects emphasize genome-wide analyses of epigenetic events contributing to the development and treatment of epigenetic-driven diseases. These projects build on our recent work, including studies on mRNA methylation (2023) and DNA methylation (2025.

We are seeking a self-motivated, career-oriented postdoctoral researcher to explore the function and dynamic regulation of mRNA and DNA methylation. The position offers a vibrant research environment and dedicated mentoring to support your scientific and professional growth.

Duties & Responsibilities
  • Responsibilities include, but are not limited to:
  • Cell culture studies.
  • Cell free, kinetic and structural studies.
  • DNA/mRNA Sequencing
  • Mentoring graduate students.
  • Manuscript and grant writing / editing.
  • Record keeping of the experiments.
  • Presenting the results at scientific meetings.
  • Participate in weekly lab meetings, Journal Clubs and common seminars within the Department.
  • Perform other related duties and participate in special projects as assigned.


  • Minimum Qualifications

    • PhD degree in Molecular Biology, Biochemistry, or a related discipline.
    • Prior research lab experience.
    • Ability to independently design and analyze research projects, with excellent manuscript/grant writing and communication skills.
    • Protein and DNA/RNA handling experience.
    • Genome editing skills.


    Preferred Qualifications
    • Experience with bioinformatics, genome editing, and high-throughput sequencing is highly desirable but not required.
    • Experience with HPLC-MS, mass spectrometry and proteomics is advantageous.




    The University of Illinois System is an equal opportunity employer, including but not limited to disability and/or veteran status, and complies with all applicable state and federal employment mandates. Please visit Required Employment Notices and Posters to view our non-discrimination statement and find additional information about required background checks, sexual harassment/misconduct disclosures, and employment eligibility review through E-Verify.

    The university provides accommodations to applicants and employees. Request an Accommodation
    Looking for more University of Illinois positions?

    We invite you to search for positions at each of the University of Illinois locations, the University of Illinois System Office and the University of Illinois Foundation. The University of Illinois System Office supports the primary missions of teaching, research, public service, and economic development for all of the Universities and offers positions in all locations. The University of Illinois Foundation is the official fundraising and private gift-receiving agency for the University of Illinois and also offers position in all locations. Click the links below to search for other University of Illinois positions.

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    The University of Illinois System is an equal opportunity employer, including but not limited to disability and/or veteran status, and complies with all applicable state and federal employment mandates. Please visit Required Employment Notices and Posters to view our non-discrimination statement and find additional information about required background checks, sexual harassment/misconduct disclosures, and employment eligibility review through E-Verify.

    To apply, visit https://uic.csod.com/ux/ats/careersite/1/home/requisition/13959?c=uic

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