Primary Duties
:
Work on a small, but collaborative team under the supervision of a Platform Head to design and execute preclinical research strategies to evaluate the efficacy and mechanism of action of mRNA candidates using primary cell cultures, immunology assays, and flow cytometry.
Responsibilities include but are not limited to:
- Perform various in vitro immunological and cellular assays on study samples and record results using an electronic lab notebook.
- Multiplex Cytokine assay.
- Design and perform phenotypic analysis by flow cytometry.
- Develop and execute immunological assay for clinical exploratory research.
- Document each experiment and relevant data in Electronic Laboratory Notebook within 1 week of data generation.
- Establish in vitro immunological and cellular assays to evaluate the biological functions of mRNA vaccine candidates in human immune cells
- Isolate primary immune cells from human whole blood, design and perform phenotypic analysis by flow cytometry.
- Participate in analyzing complex data sets integrating preclinical and clinical exploratory immune profiling.
- Independently design and execute experiment plans and interpret study observations.
- Provide guidance to more junior personnel regarding protocol development and execution.
- Effectively record and report experiments, maintaining GRP and HSE standards and policies.
- Present results in science review meetings and collaborate on project experimental study plans, reports, presentations, publications, and patents.
- Contribute to internal presentations of study data and help to answer questions and lead discussions.
Education and Experience Requirements:
- M.Sc with 3 years of experience in immunology, mRNA technology, infectious disease, or other related field (title commensurate with experience).
Key Skills, Abilities, and Competencies:
- Skilled with multiple technologies used to assess immune cell function such as in vitro immunological and cellular assays.
- Experience with primary immune cell isolation from human blood.
- Development, design and execution of experiments and interpretation of results to progress projects.
- A proactive and highly organized individual with ability to adapt quickly to evolving project needs.
- Ability to process, analyze and present data in multiple formats using various programs (Excel, FlowJo, Graph Pad, etc.).
- Ability to take ownership of work and drive projects forward.
- Presentations skills, both digitally and verbal communication formats
- The position requires work with human blood products. Personnel must abide by all immunization, occupational health, and safety requirements to handle human blood products or infectious and/or potentially infectious materials.
Other Job Requirements:
- Must have permanent US Work Authorization.
Note: Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description. All qualified applicants are welcome to apply.
Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
Visit
https://www.yoh.com/applicants-with-disabilities
to contact us if you are an individual with a disability and require accommodation in the application process.
For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment.
YOH Services LLC
Nov 21, 2024