Research Professional 5-Biomed Research

Summary of Position:

The focus of the research for the position is on the development of novel therapeutics to extend healthspan. The Robbins laboratory is part of a U19 grant identifying rare variants in centenarians linked to longevity. The role of these rare variants in conferring healthspan and longevity is being validated in mouse models. Subsequently, cell culture assays will be developed by the candidate for screening for compounds able to mimic the effect of the rare variant on key signaling pathway. The lead molecules will then be tested in animal models of aging for ability to extend healthspan.

Essential and Other Functions:

80% Laboratory Research (essential)
Cell culture, microscopy, immunoblotting, qPCR, cloning, drug development, experimental design, data analysis and recording primary data and methods used.

10% Research communication (essential)
Critical analysis of the literature, preparing manuscripts, oral presentations and posters.

10% Mentoring (secondary)
Training graduate, undergraduate and technical staff in theoretical and/or bench science

Summary of Robbins lab research:
A research position is available in the laboratory of Dr. Paul Robbins. His research program is focused on discovering fundamental mechanisms of aging. His laboratory employs a combination of genetic and pharmacologic approaches to test hypotheses about the causes of aging using murine models and primary cell populations derived from them. The laboratory is using genetic analysis of human centenarians to identify pathways important for extending human healthspan. The candidate will be developing drugs targeting these pathways are being developed and tested. The candidate will join an exciting research environment in the Department of Biochemistry, Molecular Biology and Biophysics and the newly established Institute on the Biology of Aging and Metabolism at University of Minnesota. The position offers exceptional training in aging, age-related diseases, cellular senescence, DNA damage and repair and molecular therapeutics.

Required:
-PhD in Biochemistry or a related area with specialization in cell signaling pathways, cell culture and experience working with mice with one or more years of research training
-Experience serving as an expert resource to lab members, outside collaborators, and the scientific community working on senescence, mitochondrial function and other hallmarks of aging in cell culture and in mice.

Preferred:
-Experience of successfully directing a small research group and contributing to writing papers and grants.
-Skilled in molecular biology, mammalian cell culture, confocal imaging, bioinformatics and rodent experimentation.
-Good verbal and written communication skills, the ability to work independently, and an interest in mentoring young scientists.

Working at the University

At the University of Minnesota, you'll find a flexible work environment and supportive colleagues who are interested in lifelong learning. We prioritize work-life balance, allowing you to invest in the future of your career and in your life outside of work.

The University also offers a comprehensive benefits package that includes:

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program
• Low-cost medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and employer-paid life insurance
• Employee wellbeing program
• Excellent retirement plans with employer contribution
• Public Service Loan Forgiveness (PSLF) opportunity
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost
• Employee Transit Pass with free or reduced rates in the Twin Cities metro area

Please visit the Office of Human Resources website for more information regarding benefits.

Pay Range: $60,534 - $121,808; depending on education/qualifications/experience

Time Appointment: 75%-100% Appointment

Position Type: Faculty and P&A Staff

Please visit the Office of Human Resources website for more information regarding benefit eligibility.

The University offers a comprehensive benefits package that includes:

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program
• Low-cost medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and employer-paid life insurance
• Employee wellbeing program
• Excellent retirement plans with employer contribution
• Public Service Loan Forgiveness (PSLF) opportunity
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost
• Employee Transit Pass with free or reduced rates in the Twin Cities metro area

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will have the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

This position will remain open until filled.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647.

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America's Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).